1-Pyrenyldiazomethane as a fluorescent labeling reagent for liquid chromatographic determination of carboxylic acids

N Nimura, T Kinoshita, T Yoshida, A Uetake…

Index: Nimura; Kinoshita; Yoshida; Uetake; Nakai Analytical Chemistry, 1988 , vol. 60, # 19 p. 2067 - 2070

Full Text: HTML

Citation Number: 111

Abstract

Wyrenyldlaromethane (PDAM), a new fluorescent labeling reagent, was developed for llquld chromatographic determlnation of carboxylic acld. PDAM was more stable than the other previous dlaroalkane type reagents. The reagent readily reacted with carboxylic aclds to give stable and strongly fluorescent 1-pyrenylmethyi ester derlvatlves without a catalyst and heating. PDAM derivatives of short-and long-chain fatty aclds and prostaglandins were ...