Tetrahedron

Polyhalogenated α-oxides—V: Role of steric factors in reactivity of polyfluorinated α-oxides

RA Bekker, GV Asratyan, BL Dyatkin, IL Knunyants

Index: Bekker,R.A. et al. Tetrahedron, 1974 , vol. 30, p. 3539 - 3544

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Citation Number: 4

Abstract

Steric shielding of the α-oxide 2-C-atom, as well as increase in the volume of the attacking nucleophilic agent, is shown to hinder the usual opening of polyfluorinated α-oxides at the 2- C-atom and to direct the nucleophilic attack to an other reaction centre. A mechanism of isomerisation of polyfluorinated α-oxides under the action of nucleophilic agents is suggested.