One-pot syntheses of immunostimulatory glycolipids
…, W Du, SS Kulkarni, J Gervay-Hague
Index: Schombs, Matthew; Park, Francine E.; Du, Wenjun; Kulkarni, Suvarn S.; Gervay-Hague, Jacquelyn Journal of Organic Chemistry, 2010 , vol. 75, # 15 p. 4891 - 4898
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Citation Number: 37
Abstract
Glycolipids containing α-linked galactosyl and glucosyl moieties have been shown to possess unique immunostimulatory activity creating a need for access to diverse and anomerically pure sources of these compounds for immunological studies. To meet this demand, glycosyl iodides were enlisted in the synthesis of these biologically relevant glycoconjugates. In the first-generation protocol, per-O-benzyl galactosyl iodide was ...
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