Organic letters

Diphosphine-catalyzed mixed double-Michael reaction: A unified synthesis of indolines, dihydropyrrolopyridines, benzimidazolines, tetrahydroquinolines, …

V Sriramurthy, O Kwon

Index: Sriramurthy, Vardhineedi; Kwon, Ohyun Organic Letters, 2010 , vol. 12, # 5 p. 1084 - 1087

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Citation Number: 41

Abstract

Seven different types of benzannulated N-heterocycles indolines, dihydropyrrolopyridines, benzimidazolines, dihydrobenzo-3, 1-oxazines, benzomorpholines, tetrahydroquinolines, and tetrahydroisoquinolines can be obtained from simple dinucleophiles and electron- deficient acetylenes in one synthetic step. This powerful methodology was made possible through the use of diphenylphosphinopropane (DPPP) as the catalyst, with acetic acid ...