Dioxane dibromide mediated bromination of substituted coumarins under solvent-free conditions

SK Chaudhuri, S Roy, S Bhar

Index: Chaudhuri, Subrata Kumar; Roy, Sanchita; Bhar, Sanjay Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 323 - 329

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Citation Number: 6

Abstract

Abstract An efficient solvent-free protocol for regioselective bromination of substituted coumarins has been developed by using dioxane dibromide as the solid brominating agent. The efficacy of the solvent-free protocol has been established. The effects of the electronic nature and location of the substituents on the outcome of the reaction have been rationalized with a proposed mechanism.