A novel approach to tricyclic pharmaceuticals via directed dilithiation of diaryl compounds
VB Birman, A Chopra, CA Ogle
Index: Birman, Vladimir B.; Chopra, Anu; Ogle, Craig A. Tetrahedron Letters, 1996 , vol. 37, # 29 p. 5073 - 5076
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Citation Number: 13
Abstract
Tricyclic compounds were prepared using a novel approach based on the reaction between dilithio-diphenyl ether with appropriately substituted esters. The pharmaceutical drug, clopipazan, and its corresponding deschloro analog were synthesized utilizing this approach.
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