Organic letters

Lewis base catalyzed ring opening of aziridines with silylated nucleophiles

S Minakata, Y Okada, Y Oderaotoshi, M Komatsu

Index: Minakata, Satoshi; Okada, Yuriko; Oderaotoshi, Yoji; Komatsu, Mitsuo Organic Letters, 2005 , vol. 7, # 16 p. 3509 - 3512

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Citation Number: 72

Abstract

Aziridines are very useful synthetic intermediates for the synthesis of functional materials and biologically active compounds. 1 For this reason, in previous studies, we developed some facile synthetic methods for producing aziridines through the introduction of an N1 unit to alkenes. 2 The reactivity of aziridines toward ring opening and expansion is dependent upon their extremely strained ring structures. Among the procedures of ring opening of aziridines, a ...