Tetrahedron Letters

Microwave-assisted α-halogenation of 2-methylquinolines with tetrabutylammonium iodide and 1, 2-dichloroethane (1, 2-dibromoethane)

Y Xie, L Li

Index: Xie, Yuanyuan; Li, Lehuan Tetrahedron Letters, 2014 , vol. 55, # 29 p. 3892 - 3895

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Abstract

Abstract A simple and efficient methodology permitting the halogenation of 2- methylquinolines into 2-(chloromethyl) quinolines or 2-(bromomethyl) quinolines in the tetrabutylammonium iodide and 1, 2-dichloroethane (1, 2-dibromoethane) system has been