A General and Efficient Heterogeneous Gold??Catalyzed Hydration of Nitriles in Neat Water under Mild Atmospheric Conditions

…, L He, MM Wang, Y Cao, HY He, KN Fan

Index: Liu, Yong-Mei; He, Lin; Wang, Miao-Miao; Cao, Yong; He, He-Yong; Fan, Kang-Nian ChemSusChem, 2012 , vol. 5, # 8 p. 1392 - 1396

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Citation Number: 36

Abstract

Amides constitute one of the most important functional groups in contemporary chemistry. They are essential for sustaining life, linking the amino acids in proteins such as enzymes. They are found in numerous natural products and are among the most prolific moieties in pharmaceutical molecules.[1] Despite their obvious importance, the majority of amide bond syntheses require stoichiometric amounts of coupling reagents, making them generally ...