Journal of Pharmacy and Pharmacology

Antibacterial properties of 5??nitro??2??furylglyoxylidene derivatives

WR Buckett, D Kidd

Index: Buckett,W.R.; Kidd,D. Journal of Pharmacy and Pharmacology, 1964 , vol. 16, p. 663 - 669

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Citation Number: 2

Abstract

Derivatives of 5-Nitro-2-furylglyoxal (11-X; Table 1). The general preparative method consisted of reacting the glyoxal with the amine or amine salt in ethanol or aqueous ethanol, and is illustrated by the following preparation of two of the products.(a) 5-Nitro-2-furylglyoxal (1.0 g) in ethanol (10 ml) was heated with 1-aminohydantoin hydrochloride (Jack, 1959)(0.6 g) in boiling water (2.0 ml) for 15 min. The product (11) was filtered, dried and twice ...