Improved methods for the synthesis of [ω-11C] palmitic acid

ED Hostetler, S Fallis, TJ McCarthy…

Index: Hostetler, Eric D.; Fallis, Stephen; McCarthy, Timothy J.; Welch, Michael J.; Katzenellenbogen, John A. Journal of Organic Chemistry, 1998 , vol. 63, # 4 p. 1348 - 1351

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Citation Number: 37

Abstract

The metabolism of fatty acids provides the major source of energy for the heart under normal physiological conditions. This metabolism proceeds via β-oxidation in two-carbon increments, starting at the carboxyl head and progressing along the aliphatic tail of the fatty acid. Each cycle of β-oxidation is catalyzed by a number of enzymes, including a family of acyl-CoA dehydrogenases, various members of which are specific for fatty acids of ...