Dual stimulatory and inhibitory effects of fluorine-substitution on mutagenicity: an extension of the enamine epoxide theory for activation of the quinoline nucleus.

K Saeki, H Kawai, Y Kawazoe, A HAkURA

Index: Biological and Pharmaceutical Bulletin, , vol. 20, # 6 p. 646 - 650

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Citation Number: 24

Abstract

... toxic in general due to their potent electro— philicity, leading to modification of biological macro- molecules ... 1997 Pharmaceutical Society of Japan NIT—Electronic Library Service ... 50 ul) obtained from rat liver (induced by phenobarbital and 5,6-benzofiavone, Oriental Yeast Vol. ...