Novel benzo [1, 4] diazepin-2-one derivatives as endothelin receptor antagonists

…, C Grisostomi, C Boss, C Binkert, P Hess…

Index: Bremner, John B.; Browne, Elaine J.; Gunawardana, Indrani W. K. Australian Journal of Chemistry, 1984 , vol. 37, # 1 p. 129 - 141

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Citation Number: 87

Abstract

... Journal of Medicinal ... Drug Discovery Chemistry and Preclinical Research, Actelion Pharmaceuticals Ltd., Gewerbestrasse 16, CH-4123 Allschwil, Switzerland. J. Med ... On the other hand, the ET B receptor is expressed by endothelial cells and prevails in many nonvascular tissues ...