High affinity central benzodiazepine receptor ligands. Part 3: Insights into the pharmacophore and pattern recognition study of intrinsic activities of pyrazolo [4, 3-c] …

A Carotti, C Altomare, L Savini, L Chiasserini…

Index: Bioorganic and Medicinal Chemistry, , vol. 11, # 23 p. 5259 - 5272

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Citation Number: 26

Abstract

... Bioorganic & Medicinal Chemistry. ... discriminant information and distinguishing BzR ligands with different profiles of efficacy, 51 PQ derivatives, including full and partial agonists, antagonists, and inverse agonists, were analyzed in a multidimensional chemical descriptor space ...