Organic letters

Palladium (II)-Catalyzed Conjugate Phosphination of Electron-Deficient Acceptors

VT Trepohl, S Mori, K Itami, M Oestreich

Index: Trepohl, Verena T.; Mori, Susumu; Itami, Kenichiro; Oestreich, Martin Organic Letters, 2009 , vol. 11, # 5 p. 1091 - 1094

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Citation Number: 22

Abstract

A general protocol for the conjugate transfer of diphenyl-, dicyclohexyl-, and di-tert- butylphosphinyl groups from silylphosphines to cyclic and acyclic electron-deficient acceptors employing a bench-stable palladium (II) catalyst is reported. Several E and Z configured α, β-unsaturated carbonyl and carboxyl acceptors (including imides) as well as nitroalkenes participate in this palladium (II)-catalyzed process in high chemical yields.