Synthesis of new amides of the N-methylpiperazine series

…, KN Gusak, ZV Ignatovich, AL Ermolinskaya

Index: Koroleva; Gusak; Ignatovich; Ermolinskaya Russian Journal of Organic Chemistry, 2011 , vol. 47, # 10 p. 1556 - 1563

Full Text: HTML

Citation Number: 1

Abstract

Abstract New carboxylic acid amides containing an N-methylpiperazine fragment were synthesized by reactions of 1-methylpiperazine or 3-and 4-(4-methylpiperazin-1-ylmethyl) aniline with 4-chlorobenzoyl chloride and of 4-methyl-3-nitroaniline with 4-(4- methylpiperazin-1-ylmethyl) benzoyl chloride or benzotriazol-1-yl 4-(4-methylpiperazin-1- ylmethyl) benzoate. 4-Chloro-N-[4-(4-methylpiperazin-1-ylmethyl) phenyl] benzamide ...