Acid-Mediated Specific α, α-Diarylation And A-Monoarylation Reactions Of Pyruvic Acid With/Without Decarbonylation
N Yonezawa, T Hino, T Kinuno, T Matsuki…
Index: Yonezawa, Noriyuki; Hino, Tetsuo; Kinuno, Tsuyoshi; Matsuki, Toshiyuki; Ikeda, Tomiki Synthetic Communications, 1999 , vol. 29, # 10 p. 1687 - 1695
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Citation Number: 12
Abstract
Abstract Pyruvic acid (3) was found to be arylated chemoselectively at the a-ketocarbonyl carbon in P2O5-MsOH affording decarbonylative α, α-diarylated products 5, decarbonylative a-monoarylated compounds 6, or non-decarbonylative α, α-diarylated adducts 7 depending on the reactivity of arenes (4a-g), in contrast to Lewis acid-catalyzed reaction of its acid chloride (2).
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