Synthetic communications

A Convenient Synthesis Of 1-Acyl Indolizines by 1, 3-Dipolar Cycloaddition Reactions of Pyridinium Ylides and α, β-Unsaturated Aldehydes or Ketones in the …

X Zhang, W Cao, X Wei, H Hu

Index: Zhang, Xuechun; Cao, Weili; Wei, Xudong; Hu, Hongwen Synthetic Communications, 1997 , vol. 27, # 8 p. 1395 - 1403

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Citation Number: 18

Abstract

Abstract In the presence of tetrakispyridine cobalt dichromate (CoPy4 (HCrO4) 2), pyridinium ylides and α, β-unsaturated aldehydes or ketones undergo 1, 3-dipolar cycloaddition reactions followed by in situ aromatization to give 1-acyl substituted indolizines in moderate to good yields.