Diastereoselective reduction of dimethyl γ-[(Np-toluenesulfonyl) amino]-β-ketophosphonates derived from amino acids
…, M Fernández-Zertuche, MA Muñoz-Hernández…
Index: Ordonez, Mario; De La Cruz-Cordero, Ricardo; Fernandez-Zertuche, Mario; Angel Munoz-Hernandez, Miguel; Garcia-Barradas, Oscar Tetrahedron Asymmetry, 2004 , vol. 15, # 19 p. 3035 - 3043
Full Text: HTML
Citation Number: 22
Abstract
The reduction of dimethyl γ-[(Np-toluenesulfonyl) amino]-β-ketophosphonates 7a–e with different hydrides gave dimethyl γ-[(Np-toluenesulfonyl) amino]-β-hydroxyphosphonates 9a– e and 10a–e with good chemical yield and moderated diastereoselectivity. The configuration of all new stereogenic centers were assigned by X-ray analysis and chemical correlation.
Related Articles:
Amino acids derived benzoxazepines: Design, synthesis and antitumor activity
[Dwivedi, Shailendra Kumar Dhar; Samanta, Krishnananda; Yadav, Manisha; Jana, Amit Kumar; Singh, Abhishek Kumar; Chakravarti, Bandana; Mondal, Sankalan; Konwar, Rituraj; Trivedi, Arun Kumar; Chattopadhyay, Naibedya; Sanyal, Sabyasachi; Panda, Gautam Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 24 p. 6816 - 6821]