Malonaldehyde derivatives: a general one-or two-step synthesis from substituted acetic acids

…, P Loew, P Hassel, H Bronberger

Index: Knorr, Rudolf; Loew, Peter; Hassel, Petra; Bronberger, Hildegard Journal of Organic Chemistry, 1984 , vol. 49, # 7 p. 1288 - 1290

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Citation Number: 8

Abstract

22. From cyclohexane. Reference 13. After treatment with 10. in Scheme I), which are important in heterocycli~,~-~ carbo~ yclic,~,~ and physiological'chemistry. Vilsmeier-Haack- Arnold formylation'by chloromethaniminium salb (9 or 10 in Scheme 11) to give malonaldehydes 4 is the most important of the known methods and may be applied to malonic acids, but mesityl and tert-alkyl malonic acids are merely decarboxylated under ...