Efficient Aerobic Oxidation of Acetals to Esters Catalyzed by N-Hydroxy phthalimide (NHPI) and Co (II) under Mild Conditions

B Karimi, J Rajabi

Index: Karimi, Babak; Rajabi, Jamshid Synthesis, 2003 , # 15 p. 2373 - 2377

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Citation Number: 19

Abstract

We first examined the aerobic oxidation of (dimethoxymethyl)benzene (1) as a model compound in the presence of a catalytic amount of NHPI in CH 3 CN. The reaction of 1 in the presence of NHPI (10 mol%) under O 2 (1 atm) for 20 hours afforded a trace amount of methyl benzoate (2) at room temperature. When the similar reaction was carried out using the same reagents and a catalytic amount of Co(OAc) 2 (0.5 mol%), 2 was formed with almost 70% ...