Development of a new class of chiral phosphorus ligands: P-chirogenic diaminophosphine oxides. A unique source of enantioselection in Pd-catalyzed asymmetric …

…, T Masuda, T Matsumoto, Y Hamada

Index: Nemoto, Tetsuhiro; Masuda, Takamasa; Matsumoto, Takayoshi; Hamada, Yasumasa Journal of Organic Chemistry, 2005 , vol. 70, # 18 p. 7172 - 7178

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Citation Number: 43

Abstract

We have recently developed a new class of chiral phosphorus ligands: P-chirogenic diaminophosphine oxides. These pentavalent phosphorus compounds have been successfully applied to Pd-catalyzed asymmetric construction of tertiary and quaternary carbons. The actual ligand structure was the trivalent phosphorus species 17, which was generated in situ by BSA-induced P (V) to P (III) transformation of 6, the preligand. ...