Synthesis of ω-and (ω–1)-acetylenic acids from five-, six-, or seven-membered cycloalkanones

EK Starostin, AV Ignatenko, MA Lapitskaya…

Index: Starostin; Ignatenko; Lapitskaya; Pivnitsky; Nikishin Russian Chemical Bulletin, 2001 , vol. 50, # 5 p. 833 - 837

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Citation Number: 2

Abstract

Abstract A convenient method for the synthesis of ω-and (ω–1)-acetylenic acids involves free- radical oxidative scission of cycloalkanones containing five-, six, or seven-membered cycles to give the corresponding ω-olefinic acids followed by bromination of the latter and subsequent dehydrobromination under the action of alkalis.