Tetrahedron letters

Préparation de nouveaux synthons chiraux: les β, X-époxyesters; application à la synthèse de β-hydroxyesters énantiomériquement purs

M Larchevêque, S Henrot

Index: Larcheveque, Marc; Henrot, Serge Tetrahedron Letters, 1987 , vol. 28, # 16 p. 1781 - 1782

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Citation Number: 17

Abstract

Abstract: 2'ke preparation of optically pure B, y-epoxyesters 3 has been achieved through the openingof3-hydroxybutanolides with trimethylsilyliodide follzwed by cyclisation with silver oxyde. They react with organocuprates to afford B-hydroxyesters of high enantiomerical purity.

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