Canadian journal of chemistry

Synthesis of (±)-trixagol by an electrophilic cyclization of an allylsilane

RJ Armstrong, L Weiler

Index: Armstrong, Rosemary J.; Weiler, Larry Canadian Journal of Chemistry, 1983 , vol. 61, p. 2530 - 2539

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Citation Number: 38

Abstract

1, 5-Dienes containing an allylsilane are cyclized by Lewis acids to methylenecyclohexanes. The trimethylsilyl group exerts a strong activating and directing influence on the regioselectivity of this cyclization. The monocyclic compound 10 was converted into the diterpene,(±)-trixagol (3).