Ruthenium??catalyzed synthesis of quinolines via reductive heteroannulation of nitroarenes with 3??amino??1??propanols
…, TK Kim, TJ Kim, SC Shim, NS Yoon
Index: Cho, Chan Sik; Kyung Kim, Tae; Kim, Tae-Jeong; Shim, Sang Chul; Yoon, Nam Sik Journal of Heterocyclic Chemistry, 2002 , vol. 39, # 2 p. 291 - 294
Full Text: HTML
Citation Number: 7
Abstract
Abstract Nitroarenes are reductively cyclized with 3-amino-1-propanols in dioxane/H 2 O in the presence of a ruthenium catalyst and tin (II) chloride dihydrate together with isopropanol to afford the corresponding quinolines. A reaction pathway involving initial reduction of nitroarenes to anilines, propanol group transfer from 3-amino-1-propanols to anilines, N- alkylation of anilines by 3-anilino-1-propanols and heteroannulation of 1, 3- ...
Related Articles:
Ozonolysis of quinolines: a versatile synthesis of polyfunctional pyridines
[O'Murchu, C. Synthesis, 1989 , # 11 p. 880 - 882]
[Tsuji, Yasushi; Huh, Keun-Tae; Watanabe, Yoshihisa Journal of Organic Chemistry, 1987 , vol. 52, # 9 p. 1673 - 1680]
[Cho, Chan Sik; Oh, Byoung Ho; Shim, Sang Chul Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 5 p. 1175 - 1178]
Facile synthesis of 8-substituted quinolines
[Journal of Organic Chemistry, , vol. 45, # 8 p. 1514 - 1515]
Substituent effects in the hydrolysis of quinoline-boranes
[Inorganic Chemistry, , vol. 25, p. 3291 - 3294]