Synthesis of novel oxazolyl-indoles
S Roy, S Haque, GW Gribble
Index: Roy, Sudipta; Haque, Sakhina; Gribble, Gordon W. Synthesis, 2006 , # 23 p. 3948 - 3954
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Citation Number: 17
Abstract
We describe the synthesis of oxazolyl-indoles that are structurally related to pimprinaphine. The effect of the indole N-cyanoalkyl substituents on the 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) mediated oxidation was evaluated. ... Pimprinaphine (1) is a 2,5-disubstituted (3-indolyl)oxazole that was isolated from Streptoverticillium olivoreticuli (Figure [1] ). [1] [2] The related (3-indolyl)oxazole pimprinine (2) was isolated from Streptomyces pimprina, ...
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