Catalyzed synthesis of β-amino acids esters
TV Dokichev, DR Latypova, RR Shakirov…
Index: Dokichev; Latypova; Shakirov; Biglova; Talipov Russian Journal of Organic Chemistry, 2010 , vol. 46, # 5 p. 755 - 757
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Citation Number: 4
Abstract
DOI: 10.1134/S107042801005026X β-Aminoalcohols, β-amino acids, and their esters exhibit a wide range of biological action antitumor, immunostimulating, antiphlogistic). They are used as peptidomimetics and are precursors of many synthetic and natural compounds, in particular, of β-lactams [1–4]. For instance, bestatin,[(2S, 3R)-3-amino-2-hydroxy-4- phenylbutanoyl]-L-leucine, is a specific inhibitor of the chemotoxic activity of the ...
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