Journal of the American Chemical Society

Potential Purine Antagonists. XXIV. The Preparation and Reactions of Some 8-Diazopurines1

JW Jones, RK Robins

Index: Jones; Robins Journal of the American Chemical Society, 1960 , vol. 82, p. 3773,3778

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Citation Number: 57

Abstract

The diazotization of an amino group in the “8”-position of the purine ring was first reported by Gomberg2 who described the reaction of S-aminocaffeine and nitrous acid as yielding a very unstable substance which he called “diazocaffeine.” Gomberg2 reported that this substance was obtained only in solution and was stable only at a low temperature.