Novel Synthesis of Anthelmintic Drug 4-Isothiocyanato-4′-nitrodiphenyl Ether and Its Analogs

AC Chaskar, BP Bandgar, RK Modhave…

Index: Chaskar; Bandgar; Modhave; Patil; Yewale Synthetic Communications, 2009 , vol. 39, # 6 p. 992 - 1001

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Abstract

View all references ] and agrochemicals that have antifungal and anthelmintic activities. [ 3–5 View all references ] Isothiocyanates have exhibited antitumor and antiparasitic activities [ 3 3. Posher , GHS ; Cho , CG ; Green , JV ; Zhang , Y. ; Talalay , P. Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: Correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes . J. Med. Chem. 1994 , 37 , 170 – 176 . ...