Reductive carbonylation of aryl and heteroaryl iodides using Pd (acac) 2/dppm as an efficient catalyst

AS Singh, BM Bhanage, JM Nagarkar

Index: Singh, Abhilash S.; Bhanage, Bhalchandra M.; Nagarkar, Jayashree M. Tetrahedron Letters, 2011 , vol. 52, # 18 p. 2383 - 2386

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Citation Number: 14

Abstract

Palladium catalyzed simple and efficient protocol for reductive carbonylation of aryl and heteroaryl compounds has been developed. The formylation of aryl and heteroaryl iodides takes place in the presence of Pd (acac) 2/dppm catalyst at 10bar pressure of synthetic gas to give the desired aromatic and heteroaromatic aldehydes in good to excellent yields. Easy work-up, stability of the catalyst, low catalyst loading and less reaction time are the ...