A new method for 5-(4-hydroxyphenyl) hydantoin synthesis
T Ohashi, S Takahashi, T Nagamachi…
Index: Ohashi; Takahashi; Nagamachi; et al. Agricultural and Biological Chemistry, 1981 , vol. 45, # 4 p. 831 - 838
Full Text: HTML
Citation Number: 34
Abstract
5-(4-Hydroxyphenyl) hydantoin (p-HPH), an important intermediate in production of D-2-(4- hydroxyphenyI) glycine, was synthesized by employing new amidoalkylation reaction of phenol with glyoxylic acid and urea under acidic conditions, accompanied by formation of the isomer, ie. 5-(2-hydroxyphenyl) hydantoin (o-HPH). The ratio of p-HPH was found to be mainly influenced by the reaction method (the manner of charging raw materials) and ...
Related Articles:
[Tetrahedron Asymmetry, , vol. 8, # 1 p. 85 - 92]
A new method for 5-(4-hydroxyphenyl) hydantoin synthesis
[Agricultural and Biological Chemistry, , vol. 45, # 4 p. 831 - 838]
The use of Lewis acids in the synthesis of 5-arylhydantoins
[Journal of Catalysis, , vol. 226, # 1 p. 192 - 196]
A new method for 5-(4-hydroxyphenyl) hydantoin synthesis
[Agricultural and Biological Chemistry, , vol. 45, # 4 p. 831 - 838]
A new method for 5-(4-hydroxyphenyl) hydantoin synthesis
[Agricultural and Biological Chemistry, , vol. 45, # 4 p. 831 - 838]