1-(Indolin-1-yl)-1-phenyl-3-propan-2-olamines as Potent and Selective Norepinephrine Reuptake Inhibitors

AT Vu, ST Cohn, P Zhang, CY Kim…

Index: Kucerovy; Hathaway; Mattner; Repic Synthetic Communications, 1992 , vol. 22, # 5 p. 729 - 733

Full Text: HTML

Citation Number: 12

Abstract

... Volume: Page: ... a regioselective and stereospecific epoxide ring-opening reaction of optically pure (R,R)-3-phenylglycidols 17 by indolines 13 as the key synthetic step. ... 2 , 0 °C to room temp, 12 h, 74−82%; (i) p-TsCl, TEA, CH 2 Cl 2 , 0 °C to room temp, 5 h, then ...