Synthesis of Heterocycles through a Ruthenium??Catalyzed Tandem Ring??Closing Metathesis/Isomerization/N??Acyliminium Cyclization Sequence

E Ascic, JF Jensen, TE Nielsen

Index: Ascic, Erhad; Jensen, Jakob F.; Nielsen, Thomas E. Angewandte Chemie - International Edition, 2011 , vol. 50, # 22 p. 5188 - 5191

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Citation Number: 54

Abstract

Olefin metathesis is an extremely powerful and general method for carbon–carbon bond formation in organic synthesis.[1] For example, ruthenium alkylidene catalyzed metathesis has been widely used to construct a variety of alkenes for applications in chemistry, materials science, and chemical biology. A key asset of the metathesis process is the unique olefin functional group selectivity mediated by robust and well-defined catalytic systems. ...