Generation of Arylated Quinones by Iron??Catalyzed Oxidative Arylation of Phenols: Formal Synthesis of Phellodonin, Sarcodonin ε, Leucomelone and Betulinan A
A Deb, S Agasti, T Saboo, D Maiti
Index: Deb, Arghya; Agasti, Soumitra; Saboo, Tapish; Maiti, Debabrata Advanced Synthesis and Catalysis, 2014 , vol. 356, # 4 p. 705 - 710
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Abstract
Abstract: Biologically and pharmaceutically relevant arylated quinones (Quin-Ar) have been synthesized via direct CÀH arylation of a variety of phenols using arylboronic acids. An inexpensive, environmentally friendly iron catalyst, ferric sulphate, Fe2ACHTUNGTRENNUNG (SO4) 3, was employed in this operationally simple and efficient method. Keywords: arylated quinones; arylation; iron catalysis; natural products; phenols
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