Polymerized-depolymerized vesicles. A reversible phosphatidylcholine-based membrane

SL Regen, K Yamaguchi, NKP Samuel…

Index: Regen, Steven L.; Yamaguchi, Kazuo; Samuel, N.K.P.; Singh, Maninder Journal of the American Chemical Society, 1983 , vol. 105, # 20 p. 6354 - 6355

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Citation Number: 34

Abstract

In this communication we report the synthesis and preliminary characterization of a phospholipid vesicle membrane that can be" switched on"(polymerized) and'switched off"(depolymerized) via oxidation and reduction, respectively. This membrane is based on the thiol-bearing lipid 1, 2-bis (I I-mercap1oundecanoyl) Gnglycero-3-phosphocholine (2) whose synthesis is also described herein,