Benzo [b] thiophene-2-carboxamides and benzo [b] furan-2-carboxamides are potent antagonists of the human H 3-receptor

B Peschke, S Bak, R Hohlweg, R Nielsen…

Index: Peschke, Bernd; Bak, Sonja; Hohlweg, Rolf; Nielsen, Rita; Viuff, Dorthe; Rimvall, Karin Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 12 p. 3162 - 3165

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Citation Number: 15

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Benzo[b]thiophene-2-carboxamides and benzo[b]furan-2-carboxamides have been found to be antagonists on the human histamine-3-receptor, showing a K i value of as low as 4 nM. ... Benzo[b]thiophene-2-carboxamides and benzo[b]furan-2-carboxamides are potent ...