An Efficient Selective Reduction of Aromatic Azides to Amines Employing BF3· OEt2/NaI: Synthesis of Pyrrolobenzodiazepines
A Kamal, N Shankaraiah, N Markandeya, CS Reddy
Index: Kamal, Ahmed; Shankaraiah; Markandeya; Reddy, Ch. Sanjeeva Synlett, 2008 , # 9 p. 1297 - 1300
Full Text: HTML
Citation Number: 9
Abstract
Abstract A selective and facile method for the reduction of aromatic azides to amines by employing borontrifluoride diethyl etherate and sodium iodide. This methodology has been applied towards the preparation of biologically important imine-containing pyrrolobenzodiazepines and their dilactams through intramolecular reductive-cyclization process. In this protocol the reagent systems are amenable for the generation of solution- ...
Related Articles:
[Polivka; Jilek; Holubek; et al. Collection of Czechoslovak Chemical Communications, 1984 , vol. 49, # 1 p. 86 - 109]
Catalysis and mechanistic studies of ruthenium and osmium on synthesis of anthranilic acids
[Karthikeyan; Jagadeesh, Rajenahally V.; Sree Sandhya; Puttaswamy; Nithya; Kumar, S. Senthil; Bhagat Applied Organometallic Chemistry, 2011 , vol. 25, # 1 p. 34 - 46]
Mineral deposits of the Urals and links to geodynamic evolution
[Borodina Journal of applied chemistry of the USSR, 1986 , vol. 59, # 5 pt 2 p. 1087 - 1089]
[Zhao, Haibo; Fu, Hua; Qiao, Renzhong Journal of Organic Chemistry, 2010 , vol. 75, # 10 p. 3311 - 3316]
Synthesis of new 1, 2, 3??triazolo [1, 5??a] quinazolinones
[Journal of Heterocyclic Chemistry, , vol. 47, # 2 p. 415 - 420]