Halogenated Dimefline??type Derivatives

P Valenti, M Recanatini, PD Re, L Cima…

Index: Valenti; Recanatini; da Re; Cima; Giusti Archiv der Pharmazie, 1983 , vol. 316, # 5 p. 421 - 426

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Citation Number: 6

Abstract

The introduction of halogens, especially fluorine and to a minor extent, chlorine, in biologically active compounds in order to improve their pharmacodynamic as well as pharmacokinetic properties, is a common trend in pharmaceutical The successes mainly obtained in the fields of the CNS depressants'), corticosteroid~~) and more recently in blood substitutes4) strongly support the importance of such strategy, also if the results not ...