Design and synthesis of small molecule glycerol 3-phosphate acyltransferase inhibitors

EA Wydysh, SM Medghalchi, A Vadlamudi…

Index: Journal of Medicinal Chemistry, , vol. 52, # 10 p. 3317 - 3327

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Citation Number: 36

Abstract

... Journal of Medicinal Chemistry. ... Chemistry The fundamental design of the compounds comprised structures with a negative charge at physiological pH to mimic the phosphate group of glycerol-3-phosphate and a long saturated chain to mimic the chain of palmitoyl-CoA, the ...