Tetrahedron letters

Total synthesis of 20-hydroxy-and 20-carboxy-leukotrienes B 4

KC Nicolaou, YS Chung, PE Hernandez, IM Taffer…

Index: Nicolaou, K. C.; Chung, Y. S.; Hernandez, P. E.; Taffer, I. M.; Zipkin, R. E. Tetrahedron Letters, 1986 ,  vol. 27,  # 17  p. 1881 - 1882

Full Text: HTML

Citation Number: 5

Abstract

... Abstract. The total synthesis of 20-hydroxy- and 20-carboxy-leukotrienes B 4 (1 and 2) from key intermediates 13, 14 and 15 is described. References. 1; S Shak, IM Goldstein; J. Biol. ... For a previous synthesis of these metabolites see Tetrahedron Lett., 23 (1982), p. 4751. ... All new compounds in were characterized by spectroscopic (IR, MS, UV, NMR) and analytical and/or exact mass measurements. 7; KC Nicolaou, RE Zipkin, RE Dolle, BD Harris; J. Am. Chem. ...