Synthesis of Artificial HMG-CoA Reductase Inhibitors Based on the Olefination Strategy.

T Hiyama, T Minami, K Takahashi

Index: Bulletin of the Chemical Society of Japan, , vol. 68, # 1 p. 364 - 372

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Citation Number: 37

Abstract

... by asymmetric reduction of /?,£-diketo esters derived from the Taber's alcohol or L-tartrate followed by a series of chemical transformations, and ... Jpn., 68, No. 1 (1995) Artificial HMG-CoA Reductase Inhibitor NK-104 Table 1. Olefination of (±)-4a with reagent 3b Preparation of 3b ...

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