Tetrahedron

Regioselective propargylation of aldehydes and ketones by electrochemical reaction using zinc and aluminum anodes

N Kurono, K Sugita, M Tokuda

Index: Kurono, Nobuhito; Sugita, Kazuya; Tokuda, Masao Tetrahedron, 2000 , vol. 56, # 6 p. 847 - 854

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Citation Number: 19

Abstract

Electrochemical propargylation of aldehydes and ketones with unsubstituted or α-substituted propargylic bromides using platinum cathode and zinc anode proceeded efficiently under mild conditions to give the corresponding homopropargyl alcohols exclusively in high yields. Similar electrochemical propargylation with γ-substituted propargyl bromides gave the corresponding homoallenyl alcohols as major products. Regioselectivity in the ...

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