Synthesis of bis-spirofused thiapyrrolizidinooxindoles by 1, 3-dipolar cycloaddition

…, YV Nelyubina, KA Lyssenko, SV Kurbatov

Index: Shvets; Nelyubina; Lyssenko; Kurbatov Russian Chemical Bulletin, 2012 , vol. 61, # 8 p. 1659 - 1662

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Citation Number: 4

Abstract

Abstract The 1, 3-dipolar cycloaddition of unstabilized azomethine ylide, which is generated in situ from isatin and thiaproline, to arylidene derivatives of rhodanine affords bis-spirofused thiapyrrolizidinooxindoles. The 1, 3-dipolar addition reactions under consideration are fully regio-and diastereoselective.