Intramolecular Nonbonded S⊙⊙⊙ O Interaction Recognized in (Acylimino) thiadiazoline Derivatives as Angiotensin II Receptor Antagonists and Related …

Y Nagao, T Hirata, S Goto, S Sano…

Index: Nagao, Yoshimitsu; Hirata, Terukage; Goto, Satoru; Sano, Shigeki; Kakehi, Akikazu; Iizuka, Kinji; Shiro, Motoo Journal of the American Chemical Society, 1998 , vol. 120, # 13 p. 3104 - 3110

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Citation Number: 176

Abstract

The intramolecular nonbonded 1, 5-type S⊙⊙⊙ O interactions are recognized in the crystalline structures of the (acylimino) thiadiazoline derivatives (1-3) as angiotensin II receptor antagonists. The relative stability of the nonbonded 1, 5-type S⊙⊙⊙ O interaction was investigated using the X-ray crystallographic analyses and the ab initio MO calculations (HF/3-21G*, 6-31G*, and 6-311+ G**) of the simplified model compounds (6, 7, and 9). ...