Tetrahedron Letters

Preparation of α, β-unsaturated esters and amides via external-CO-free palladium-catalyzed carbonylation of alkenyl tosylates

T Ueda, H Konishi, K Manabe

Index: Ueda, Tsuyoshi; Konishi, Hideyuki; Manabe, Kei Tetrahedron Letters, 2012 , vol. 53, # 38 p. 5171 - 5175

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Citation Number: 22

Abstract

Palladium-catalyzed carbonylation of tosylates with phenyl formate is described. This procedure needs neither external carbon monoxide nor any pressure-resistant apparatus. A variety of cyclic and acyclic alkenyl tosylates can be converted into the corresponding phenyl esters in good yields. Furthermore, this method is effective for the one-pot synthesis of α, β-unsaturated amides.