Journal of the American Chemical Society

Enantioselective synthesis of pentacycloanammoxic acid

V Mascitti, EJ Corey

Index: Mascitti, Vincent; Corey Journal of the American Chemical Society, 2006 , vol. 128, # 10 p. 3118 - 3119

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Citation Number: 67

Abstract

A highly effective enantioselective synthesis of pentacycloanammoxic acid (1), an unusual naturally occurring fatty acid from Candidatus Brocadia anammoxidans, has been accomplished. The C20-structure of 1 was assembled with stereocontrol from four building blocks, cyclobutene, 2-cyclopentenone, the chiral silylcyclopentenone 6, and 7- bromoheptanoic acid. Both 1 and its enantiomer are now available in quantities that ...