Quinazolines. VI. The Alkylation of Benzoylene Urea

NA Lange, FE Sheibley

Index: Lange; Sheibley Journal of the American Chemical Society, 1933 , vol. 55, p. 2113,2114

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Citation Number: 3

Abstract

The greater reactivity of substituents in the 4-position of quinazoline as compared with similar or like substituents in the 2-position has been demonstrated in previous papers. When benzoylene urea (2, 4-diketotetrahydroquinazoline) is alkylated with alkyl iodides in the presence of caustic alkalies a corresponding difference in the reactivities of the two imino hydrogen atoms present in this substance is noticed, the alkyl group invariably ...