Comptes Rendus Chimie

Highly effective and regioselective Michael addition of indoles to α, β-unsaturated ketones promoted by pentafluorophenylammonium triflate

S Khaksar, SM Vahdat, F Rezaee

Index: Khaksar, Samad; Vahdat, Seyed Mohammad; Rezaee, Fatemeh Comptes Rendus Chimie, 2013 , vol. 16, # 2 p. 144 - 147

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Citation Number: 3

Abstract

A simple, inexpensive, environmentally friendly and efficient route for Michael addition of indoles to α, β-unsaturated ketones using pentafluorophenylammonium triflate (PFPAT) as a catalyst is described. Various indole derivatives were synthesized in good to excellent yields. The preparation of PFPAT catalyst from simple and readily available starting materials makes this method more affordable.