Tetrahedron

Studies on the chemistry of 2-(2-oxo-3-phenylpropyl)-benzaldehydes: novel total synthesis of 3-phenylnaphthalen-2-ols and 2-hydroxy-3-phenyl-1, 4- …

A Martínez, M Fernández, JC Estévez, RJ Estévez…

Index: Martinez, Ana; Fernandez, Marcos; Estevez, Juan C.; Estevez, Ramon J.; Castedo, Luis Tetrahedron, 2005 , vol. 61, # 2 p. 485 - 492

Full Text: HTML

Citation Number: 21

Abstract

We describe the first studies on the chemistry of 2-(2-oxo-3-phenylpropyl) benzaldehydes, which were converted into 3-benzylisochromen-1-ones via the corresponding 2-(2-oxo-3- phenylpropyl) benzoic acid. The 2-(2-oxo-3-phenylpropyl) benzaldehydes proved to be convenient starting materials for the synthesis of 3-phenyl-2-naphthols. Oxidation of the latter compounds resulted in a novel, efficient synthesis of 3-phenyl-1, 2-naphthoquinones ...